Product Description

KCNN3 (SK3) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30730-50, RA30730-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: potassium calcium-activated channel subfamily N member 3 (KCNN3) Homo sapiens Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript v

Reactivity: Human, Rat

Host: Rabbit

Applications: IHC-p, IF (paraffin section)

Alternate Names: Small conductance calcium-activated potassium channel protein 3 (SK3;SKCa 3;SKCa3;KCa2.3), YM3566

Clonality: Polyclonal

Dilution: IHC 1:100-200

Molecular Weight: 82

Protein Molecular Weight (kDa): 82

Storage: -20°C/1 year

Human Gene ID: 3782

Human SwissProt Number: Q9UGI6

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only