KCNQ4 Polyclonal Antibody - RA26620

KCNQ4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26620-50, RA26620-100

Citations, Manuals and MSDS Available upon request.

Background: potassium voltage-gated channel subfamily Q member 4 (KCNQ4) Homo sapiens The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: KCNQ4; Potassium voltage-gated channel subfamily KQT member 4; KQT-like 4; Potassium channel subunit alpha KvLQT4; Voltage-gated potassium channel subunit Kv7.4

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 9132

Protein MW (KDa): 80

SWISS: P56696

Source: Rabbit

Research Use Only