KCNT1 rabbit pAb - ES6922

KCNT1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6922-50, ES6922-100

Citations, Manuals and MSDS Available upon request.

Background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],

Alternate Name: KCNT1; KIAA1422; Potassium channel subfamily T member 1; KCa4.1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human KCNT1. AA range:1019-1068

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 140kD

Human Gene ID: 57582

Human SWISS Prot NO: Q5JUK3

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only