Product Description

KCTD21 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46925-50, BS46925-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Probable substrate-specific adapter of a BCR (BTB-Cμl3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1, the function probably occurs via HDAC1 down-regμlation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medμlloblastoma (MDB) (PubMed:21472142).

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, FC

Alternate Names: KCASH2

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human KCTD21

Dilution: WB: 1:1000 FC: 1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 30 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q4G0X4

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only