[KD Validated] MRPL53 Rabbit pAb - A25249

[KD Validated] MRPL53 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A25249-20, A25249-100

Citations, Manuals and MSDS Available upon request.

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 1p.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human

Protein Weight: 12kDa

Observed Molecular Weight: 12kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 116540

SWISS: Q96EL3

Alternate Names: mL53; L53MT

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Mitochondrial.

NCBI Alias: MRPL53

Research Use Only