[KD Validated] MTMR3 Rabbit pAb - A10806

[KD Validated] MTMR3 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A10806-20, A10806-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol (3) -phosphate and phosphatidylinositol (3, 5) -biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human

Protein Weight: 134kDa

Observed Molecular Weight: 130-150kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 8897

SWISS: Q13615

Alternate Names: ZFYVE10; FYVE-DSP1; [KD Validated] MTMR3

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, Cell Biology Developmental Biology, Autophagy.

NCBI Alias: MTMR3

Research Use Only