KDM3B Polyclonal Antibody - BT-AP10662

KDM3B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10662-20, BT-AP10662-50, BT-AP10662-100

Citations, Manuals and MSDS Available upon request.

Background: cofactor:Binds 1 Fe(2+) ion per subunit.,Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.,Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.,miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del(5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del(5q) tumor suppressor gene.,Belongs to the JHDM2 histone demethylase family.,Contains 1 JmjC domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.,

Research Areas: Cancer; Epigenetics and nuclear signaling

Target Protein: KDM3B

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Lysine-specific demethylase 3B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q7LBC6; Mouse: Q6ZPY7

Synonyms: Lysine-specific demethylase 3B;EC 1.14.11.-;JmjC domain-containing histone demethylation protein 2B;Jumonji domain-containing protein 1B;Nuclear protein 5qNCA

GeneID: Human: 51780

Research Use Only