Product Description

KDM3B Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32936-50, RA32936-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: cofactor:Binds 1 Fe (2+) ion per subunit., domain:Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors., function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity., miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del (5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del (5q) tumor suppressor gene., similarity:Belongs to the JHDM2 histone demethylase family., similarity:Contains 1 JmjC domain., tissue specificity:Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 193

Protein Molecular Weight (kDa): 193

Storage: -20°C/1 year

Human Gene ID: 51780

Human SwissProt Number: Q7LBC6

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only