Product Description

KDM3B Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32936-50, RA32936-100

Citations, Manuals and MSDS Available upon request.

Background: cofactor:Binds 1 Fe (2+) ion per subunit.,domain:Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.,miscellaneous:Its gene is located in the 5q region of the genome which is deleted in del (5q) interstitial deletion, a frequent deletion found in myeloid leukemias and myelodysplasias, suggesting that it may be a good candidate for the del (5q) tumor suppressor gene.,similarity:Belongs to the JHDM2 histone demethylase family.,similarity:Contains 1 JmjC domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.,

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 51780

Protein MW (KDa): 193

SWISS: Q7LBC6

Source: Rabbit

Research Use Only