Product Description

KDM4A Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16953-50, BZ16953-100

Swiss-Prot: O75164

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, IP

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Calculated MW: 121 kDa; Observed MW: 150 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of KDM4A / JHDM3A / JMJD2A in HEK293 lysates; NIH3T3 lysates using KDM4A antibody.

Alternative Name: KDM4A; JHDM3A; JMJD2; JMJD2A; KIAA0677; Lysine-specific demethylase 4A; JmjC domain-containing histone demethylation protein 3A; Jumonji domain-containing protein 2A

Immunogen: A synthesized peptide derived from human KDM4A / JHDM3A / JMJD2A

Conjugate: Unconjugated

Modification: Unmodified