KDM5B Polyclonal Antibody - BT-AP10665

KDM5B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10665-20, BT-AP10665-50, BT-AP10665-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing resultsi n multiple transcript variants.

Research Areas: Epigenetics and nuclear signaling

Target Protein: KDM5B

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Lysine-specific demethylase 5B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9UGL1; Mouse: Q80Y84

Synonyms: Lysine-specific demethylase 5B;EC 1.14.11.-;Cancer/testis antigen 31;CT31;Histone demethylase JARID1B;Jumonji/ARID domain-containing protein 1B;PLU-1;Retinoblastoma-binding protein 2 homo

GeneID: Human: 10765

Research Use Only