Product Description

Keap1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12091-50, MB12091-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q14145

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 70 kDa; Observed MW: 60-64 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Keap1 in Raw264.7 lysates using Keap1 antibody., Western blot analysis of Keap1 in Hela, A549, C2C12 lysates using Keap1 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Keap1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: INrf2; KLHL19

Immunogen: Recombinant protein of human Keap1

Conjugate: Unconjugated

Modification: Unmodified