Keratin 8 rabbit pAb - ES8894

Keratin 8 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8894-50, ES8894-100

Citations, Manuals and MSDS Available upon request.

Background: keratin 8 (KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

Alternate Name: Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human Keratin 8 Polyclonal

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 53kD

Human Gene ID: 3856

Human SWISS Prot NO: P05787

Subcellular Location: Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.

Research Use Only