KHSRP Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB9324-50, MB9324-100
Product: Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q92945(Human) Q3U0V1(Mouse) Q99PF5(Rat)
Host: Mouse
Reactivity: Human, Mouse, Rat
Applications: WB, FC
All Applications: WB:1:500-1:2,000
FC:1:50-1:100
Background: Binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Purification and Purity: ProG purified.
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: KHSRP monoclonal antibody detects endogenous levels of KHSRP protein.
Bioworld Molecular Weight: 73 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of KHSRP on Jurkat cell lysate using anti-KHSRP antibody at 1/500 dilution., Flow cytometric analysis of HT-29 cells with KHSRP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.
Alternative Name: FUSE-binding protein 2, KSRP, KHSRP, FUBP2, Far upstream element-binding protein 2, FBP2, FUBP2, FUBP2, FUSE binding protein 2, FUSE-binding protein 2, KH type splicing regulatory protein (FUSE binding protein 2), KH type splicing regulatory protein, KH type-splicing regulatory protein, KHSRP, KSRP, p75,
Immunogen: Synthetic peptide within human KHSRP aa 600-700.
Conjugate: Unconjugated
Modification: Unmodified