Ki 67 Mouse mAb - EM1064

Ki 67 Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1064-50, EM1064-100

Citations, Manuals and MSDS Available upon request.

Background: Antigen KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis. The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0).

Alternate Name: KIA, MKI67

Source: Mouse

Applications: IHC

Dilution: IHC 1:200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Human Gene ID: 4288

Human SWISS Prot NO: P46013

Subcellular Location: Chromosome, Nucleus

Research Use Only