Product Description

Ki-67 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS9931M-50, BS9931M-100

Swiss-Prot: P46013

Host: Rabbit

Ki-67 Polyclonal Antibody-BS9931M

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB 1:500 - 1:2000
IF 1:50 - 1:200

Background: Ki-67 is a nuclear protein that is expressed in proliferating cells and may be required for maintaining cell proliferation. Ki-67 has been used as a marker for cell proliferation of solid tumors and some hematological malignancies. A correlation has been demonstrated between Ki-67 index and the histopathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Ki-67 polyclonal antibody detects endogenous levels of Ki-67 protein.

Bioworld Molecular Weight: ~ 359 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using Ki67 antibody at 1:500 dilution., Immunofluorescence analysis of HeLa cells using Ki67 antibody.

Alternative Name: Antigen KI-67; MKI67; Ki67; Ki 67

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human Ki67 (NP_001139438.1).

Modification: Unmodified

Conjugate: Unconjugated