KI67 Monoclonal Antibody - BT-MCA3414

KI67 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3414-50, BT-MCA3414-100

Citations, Manuals and MSDS Available upon request.

Background: Ki67, also known as MKI67, it is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

Research Areas: Others

Target Protein: KI67

Applications: WB, IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8D5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: KI67

Immunogen: Synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 358kDa

UniProt Accession: P46013

Synonyms: KIA, Ki-67, MKI67

GeneID: 4288

Research Use Only