Product Description

KIF1B Monoclonal Antibody

Catalogue Numbers: MB66727-50, MB66727-100

Sizes: 50µl, 100µl

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: O60333

Host: Mouse

Reactivity: Human, Rat

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36.22. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype.The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of KIF1B protein.

Extra Notes: Western blot analysis of KIF1B expression in Hela (A), PC3 (B) whole cell lysates.

Bioworld Molecular Weight: ~ 130 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: KIAA0591; KIAA1448; Kinesin-like protein KIF1B; Klp

Immunogen: Recombinant fusion protein of human KIF1B. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified