Product Description

KIF1B Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66727-50, MB66727-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The kinesins constitute a large family of microtubμle-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecμlar complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellμlar transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36.22. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype.The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Mouse

Applications: WB

Alternate Names: KIAA0591, KIAA1448, Kinesin-like protein KIF1B, Klp

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human KIF1B. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of KIF1B protein.

Molecular Weight: ~ 130 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O60333

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only