Product Description

KIF2B Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8251-50, BS8251-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The kinesins constitute a large family of microtubμle-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecμlar complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellμlar transport and membrane trafficking events including endocytosis and transcytosis. KIF2B (kinesin family member 2B) is a 673 amino acid cytoplasmic protein that localizes to the kinetochore. Highly expressed in lung and ovary with moderate expression in heart, kidney, placenta skeletal muscle and spleen, KIF2B has microtubμle depolymerization activity and is associated with peripheral translocation of lysosomes. Overexpression of KIF2B in cells resμlt in abnormally large lysosome size and unusual positioning, which is some distance from their usual perinuclear location. KIF2B activity is critical for spindle assembly and chromosome movement.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Kinesin-like protein KIF2B, KIF2B

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human KIF2B.

Dilution: WB 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: KIF2B polyclonal antibody detects endogenous levels of KIF2B protein.

Molecular Weight: ~ 76 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8N4N8

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only