Product Description

KIF2C (phospho-S95) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67093-50, BS67093-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: In complex with KIF18B, constitutes the major microtubμle plus-end depolymerizing activity in mitotic cells (PubMed:21820309).Regμlates the turnover of microtubμles at the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894).Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubμle attachment (PubMed:23891108).

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IF/ICC

Alternate Names: KNSL6, Kinesin-like protein KIF2C, Kinesin-like protein 6, Mitotic centromere-associated kinesin, MCAK

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human KIF2C. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000), IF/IC (1/100 - 1/500)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of KIF2C (pS95) protein.

Molecular Weight: ~ 90 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q99661

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only