KIF2C (phospho Ser95) rabbit pAb - ES4579

KIF2C (phospho Ser95) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4579-50, ES4579-100

Citations, Manuals and MSDS Available upon request.

Background: kinesin family member 2C (KIF2C) Homo sapiens This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Alternate Name: KIF2C; KNSL6; Kinesin-like protein KIF2C; Kinesin-like protein 6; Mitotic centromere-associated kinesin; MCAK

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human KIF2C around the phosphorylation site of Ser95. AA range:61-110

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 80kD

Human Gene ID: 11004

Human SWISS Prot NO: Q99661

Subcellular Location: Cytoplasm, cytoskeleton. Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Association with microtubule plus ends is also mediated by interaction with KIF18B. Centromeric localization requires the presence of BUB1 and SGO2.

Research Use Only