KIF5B Monoclonal Antibody-MB11146

KIF5B Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11146-50, MB11146-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P33176

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner . Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation .

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 110 kDa; Observed MW: 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of KIF5B in mouse brain, rat brain lysates using KIF5B antibody., Western blot analysis of KIF5B in Hela, MCF-7, U251MG, K562 lysates using KIF5B antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using KIF5B antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunocytochemistry analysis of KIF5B in Hela using KIF5B antibody, and DAPI.

Alternative Name: KNS; KINH; KNS1; UKHC; HEL-S-61

Immunogen: A synthetic peptide of human KIF5B

Conjugate: Unconjugated

Modification: Unmodified