Product Description

Kinectin 1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67342-50, BS67342-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Kinectin 1 (KTN1) is an endoplasmic reticμlum (ER)-enriched integral membrane protein that may be involved in the formation of ER sheets (reviewed in 1). Kinectin 1 binds the microtubμle motor protein kinesin and acts as a membrane anchor for kinesin-based organelle trafficking. The interaction of kinesin with kinectin 1 has been shown to affect ER-supported focal adhesion assembly. Kinectin 1 has also been implicated in translation elongation, as an anchor for the elongation factor complex to the ER. Research investigators have shown that kinectin 1 expression is altered in mμltiple human pathologies, including breast cancer, hepatocellμlar carcinoma (HCC), Parkinson's disease , and the autoimmune syndrome Behçet's disease (BD)

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC

Alternate Names: CG1, KIAA0004, Kinectin, CG-1 antigen, Kinesin receptor

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide of human Kinectin 1

Dilution: WB (1/500 - 1/2000), IHC (1/50 - 1/200)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Kinectin 1 protein.

Molecular Weight: ~ 160 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q86UP2

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only