Product Description

KIR2.1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21129-50, RA21129-100

Citations, Manuals and MSDS Available upon request.

Background: potassium voltage-gated channel subfamily J member 2 (KCNJ2) Homo sapiens Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: KCNJ2; IRK1; Inward rectifier potassium channel 2; Cardiac inward rectifier potassium channel; Inward rectifier K (+) channel Kir2.1; IRK-1; hIRK1; Potassium channel; inwardly rectifying subfamily J member 2

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Rat

GeneID (Human): 3759

Protein MW (KDa): 48

SWISS: P63252

Source: Rabbit

Research Use Only