Kir3.4 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90772-50, BS90772-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P48544(Human) P48545(Mouse) P48548(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC IHC FC
All Applications: WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.
Purification and Purity: Peptide affinity purified.
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: Kir3.4 polyclonal antibody detects endogenous levels of Kir3.4 protein.
Bioworld Molecular Weight: 48 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Kir3.4 on different lysates using anti-Kir3.4 antibody at 1/500 dilution.
Positive control:
Lane 1: Mouse heart
Lane 2: Rat heart, ICC staining Kir3.4 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: GIRK-4, CIR, IRK-4, KCNJ5, GIRK4, Cardiac ATP sensitive potassium channel, Cardiac inward rectifier, CIR, G protein activated inward rectifier potassium channel 4, G protein-activated inward rectifier potassium channel 4, GIRK 4, GIRK-4, GIRK4, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, Inward rectifier K+ channel KIR3.4, Inward rectifier potassium channel KIR3.4, inwardly rectifying subfamily J member 5, IRK-4, IRK5, KATP 1, KATP-1, KATP1, KCNJ 5, Kcnj5, KIR 3.4, KIR3.4, LQT13, Potassium channel, Potassium channel inwardly rectifying subfamily J member 5, Potassium inwardly rectifying channel J5, Potassium inwardly rectifying channel subfamily J member 5, potassium voltage-gated channel subfamily J member 5,
Immunogen: Synthetic peptide within N-terminal human Kir3.4.
Conjugate: Unconjugated
Modification: Unmodified