KIR6.2 (phospho Thr224) Polyclonal Antibody - RA26668

KIR6.2 (phospho Thr224) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26668-50, RA26668-100

Citations, Manuals and MSDS Available upon request.

Background: potassium voltage-gated channel subfamily J member 11 (KCNJ11) Homo sapiens Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM) . Multiple alternatively spliced trans

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: KCNJ11; ATP-sensitive inward rectifier potassium channel 11; IKATP; Inward rectifier K (+) channel Kir6.2; Potassium channel; inwardly rectifying subfamily J member 11

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 3767

Protein MW (KDa): 40

SWISS: Q14654

Source: Rabbit

Research Use Only