Product Description

KIRREL2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60707-50, BS60707-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: NEPH3 (nephrin-like protein 3), also referred to as NLG1, FILTRIN or KIRREL2 (kin of IRRE like 2), is a 708 amino acid protein that is a member of the immunoglobμlin superfamily of cell adhesion molecμles. NEPH3 consists of five extracellμlar Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues. NEPH3 localizes to the interpodocyte filtration slit in the kidney and to the Langerhans islet beta cells in the pancreas. NEPH3 is thought to be involved in the maintenance of the glomerμlar filtration barrier in the kidney and in pancreas development. Downregμlation of NEPH3 is implicated in several proteinuric diseases. Five isoforms exists due to alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB

Alternate Names: Kin of IRRE-like protein 2, Kin of irregμlar chiasm-like protein 2, Nephrin-like protein 3, KIRREL2NEPH3, UNQ5827, PRO19646

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human KIRREL2

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: KIRREL2 polyclonal antibody detects endogenous levels of KIRREL2 protein.

Molecular Weight: ~ 75 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q6UWL6

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only