KIT Monoclonal Antibody - BT-MCA2497

KIT Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2497-50, BT-MCA2497-100

Citations, Manuals and MSDS Available upon request.

Background: The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

Research Areas: Immunology

Target Protein: KIT

Applications: WB, IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1C5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: KIT

Immunogen: Purified recombinant fragment of human KIT expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 145kDa

UniProt Accession: P10721

Synonyms: PBT, SCFR, C-Kit, CD117

GeneID: 3815

Research Use Only