KLHL12 Monoclonal Antibody - RA11576

KLHL12 Monoclonal Antibody Size: 50μL, 100μL Catalogue Numbers: RA11576-50, RA11576-100 Citations, Manuals and MSDS Available upon request. Background: kelch like family member 12 (KLHL12) Homo sapiens This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014], Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol. Storage Instructions: -20°C/1 year Applications: WB; ELISA Species Cross-Reactivity: Human GeneID (Human): 59349 SWISS: Q53G59 Source: Mouse Research Use Only