Product Description

KLK11 Polyclonal Antibody

Catalogue Numbers: BS60012-50, BS60012-100

Sizes: 50µl, 100µl

Alternative Name: Kallikrein-11; Kallikrein11; Kallikrein 11; hK11; Hippostasin; Serine protease 20; Trypsin-like protease; Kallikrein-11 inactive chain 1; Kallikrein-11 inactive chain 2; PRSS20; TLSP; UNQ649/PRO1279

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9UBX7

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: The human KLK genes are clustered on chromosome 19q13. Unlike other kalllikreins, the KLK4-15 encoded proteases are less related and do not contain a conventional KLK loop. Clusters of genes exhibit high prostatic (KLK2-4, KLK15) or pancreatic (KLK6-13) expression. KLK2 is also known as glandular kallikrein 2, tissue kallikrein or HGK-1, and KLK3 is known as prostate-specific antigen (PSA). Both KLK2 and KLK3 have important applications in prostate cancer and breast cancer diagnostics. KLK4, KLK5, KLK9, KLK13, KLK12 and KLK14 have been previously known as KLK-L1, KLK-L2, KLK-L3, KLK-L4, KLK-L5 and KLK-L6, respectively. Many of the KLKs are regulated by steroid hormones and a few of them, specifically KLK3, KLK6 and KLK10, are known to be downregulated in breast and other cancers.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KLK11 polyclonal antibody detects endogenous levels of KLK11 protein.

Bioworld Molecular Weight: ~ 32 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of KLK11 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: Rat brain tissue lysate

Immunogen: A synthetic peptide corresponding to residues in Human KLK11.

Conjugate: Unconjugated

Modification: Unmodified