Product Description

KLK9 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65850-50, BS65850-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fμlly mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in cμlture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The fμll length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Horse

Host: Rabbit

Applications: IHC-P

Alternate Names: Kallikrein 8, Kallikrein 9, Kallikrein L3, Kallikrein Like 3, Kallikrein like protein 3, kallikrein related peptidase 9, Kallikrein-9, Kallikrein-like protein 3, Kallikrein8, Kallikrein9, KLK 8, KLK 9, KLK L3, KLK-L3, KLK8, KLK9, KLK9_HUMAN, KLKL 3, KLKL3.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human KLK9:51-150/250

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: KLK9 Polyclonal Antibody detects endogenous levels of KLK9 protein.

Molecular Weight: ~26kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -23°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UKQ9

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only