KLOT rabbit pAb - ES11915

KLOT rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11915-50, ES11915-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from part region of human protein AA range: 400-500

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 111kD

Human Gene ID: 9365

Human SWISS Prot NO: Q9UEF7

Subcellular Location: [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Apical cell membrane; Single-pass type I membrane protein. Isoform 1 shedding leads to a soluble peptide.; [Isoform 2]: Secreted.; [Klotho peptide]: Secreted.

Research Use Only