Product Description

KLOTB Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32989-50, RA32989-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: domain:Contains 2 glycosyl hydrolase 1 regions. However, the first region lacks the essential Glu active site residue at position 241, and the second one lacks the essential Glu active site residue at position 889. These domains are therefore predicted to be inactive., function:Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21., similarity:Belongs to the glycosyl hydrolase 1 family., similarity:Belongs to the glycosyl hydrolase 1 family. Klotho subfamily., subunit:Interacts with FGFR1 and FGFR4.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 114

Protein Molecular Weight (kDa): 114

Storage: -20°C/1 year

Human Gene ID: 152831

Human SwissProt Number: Q86Z14

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only