Product Description

KMT4 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12094-50, MB12094-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q8TEK3

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 165 kDa; Observed MW: 185 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry analysis of paraffin-embedded mouse testis using KMT4 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Western blot analysis of KMT4/Dot1L in Hela, A549, HL-60 lysates using KMT4/Dot1L antibody.

Alternative Name: DOT 1; DOT1L; KMT4; Histone methyltransferase DOT1L; H3 lysine-79 specific

Immunogen: Recombinant protein of human KMT4/Dot1L

Conjugate: Unconjugated

Modification: Unmodified