[KO Validated] BAF57/SMARCE1 Rabbit pAb - A13353

[KO Validated] BAF57/SMARCE1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A13353-20, A13353-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, IP, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 47kDa

Observed Molecular Weight: 50kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 6605

SWISS: Q969G3

Alternate Names: CSS5; BAF57; E1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Chromatin Remodeling.

NCBI Alias: SMARCE1

Research Use Only