[KO Validated] RhoC Rabbit pAb - A1062

[KO Validated] RhoC Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A1062-20, A1062-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Rat

Protein Weight: 22kDa

Observed Molecular Weight: 22kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 389

SWISS: P08134

Alternate Names: H9; ARH9; ARHC; RHOH9; oC

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol,  preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Microtubules.

NCBI Alias: RHOC

Research Use Only