Product Description

KOR-1 (Ab-369) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65124-50, BS65124-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: opioid receptor kappa 1(OPRK1) Homo sapiens This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding resμlts in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jan 2016],

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Applications: WB, ELISA

Alternate Names: OPRK1, OPRK, Kappa-type opioid receptor, K-OR-1, KOR-1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: The antiserum was produced against synthesized peptide derived from human OPRK1. AA range:321-370

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.

Molecular Weight: ~ 48 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P41145

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only