KOR-1 (phospho Ser369) Polyclonal Antibody - RA26699

KOR-1 (phospho Ser369) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26699-50, RA26699-100

Citations, Manuals and MSDS Available upon request.

Background: Endogenous opioid peptides and opiates, like morphine, transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor, mu-type, delta-type and kappa-type, also designated MOR-1, DOR-1 and KOR-1, respectively. MOR-1 is a receptor for beta-endorphin, DOR-1 is a receptor for enkephalins, and KOR-1 is a receptor for dynorphins.The three opioid receptor types are highly homologous and belong to the superfamily of G-protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions, including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Mouse; Rat

Protein MW (KDa): 42

Source: Rabbit

Research Use Only