KPNA6 Rabbit Polyclonal Antibody - RA32996

KPNA6 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32996-50, RA32996-100

Citations, Manuals and MSDS Available upon request.

Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.07% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IP: 2-10µg/mL WB 1:500-2000

Alternative Names: Importin subunit alpha-7 (Karyopherin subunit alpha-6)

Applications: WB; IP

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 23633

Protein MW (KDa): 60

SWISS: O60684

Source: Rabbit

Research Use Only