KPNB1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-13334-60, E-AB-13334-120, E-AB-13334-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: KPNB1
Target Synonym: IMB 1; IMB1; IMB1; Impnb; Importin 90; Importin beta 1; Importin beta 1 subunit; Importin subunit beta-1; Importin-90; IPOB; Karyopherin beta 1; Karyopherin beta 1 subunit; Karyopherin subunit beta-1; KPNB 1; Kpnb1; MGC2155; MGC2156; MGC2157; NTF 97; NTF97; Nuclear factor P97; Pore targeting complex 97 kDa subunit; PTAC97
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction, Tags and Cell Markers
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q14974
Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.
Concentration: 1 mg/mL
Immunogen: Synthetic peptide of human KPNB1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only