KRR1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-52736-60, E-AB-52736-120, E-AB-52736-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: KRR1
Target Synonym: HIV 1 Rev binding protein 2; HIV-1 Rev-binding protein 2; HRB2; KRR1; KRR1 small subunit processome component homolog; KRR1; small subunit (SSU) processome component; homolog (yeast); KRR1; Rev interacting protein 1; Rev-interacting protein 1; RIP 1 ; Rip-1
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology, Tags and Cell markers
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q13601
Background: The SSU is a large ribonucleoprotein consisting of at least 40 proteins and the U3 small nucleolar RNA. It is involved in pre-rRNA processing and ribosome assembly. The SSU is necessary for the biogenesis of the 18S rRNA. Cells that are depleted of SSU proteins will arrest in the G1 phase of the cell cycle. KRR1, also known as HRB2 (HIV-1 Rev binding protein 2) or RIP-1 (Rev interacting protein 1), is a nonribosomal component of the small subunit processome (SSU). KRR1 is 381 amino acids in length and is evolutionarily conserved among human, yeast, fly, nematode and rice. KRR1 localizes to the nucleolus and is highly expressed in dividing cells. It contains one conserved KH domain (RNA-binding motif) and is a crucial component of the SSU, required for both rRNA maturation and ribosome biogenesis.
Concentration: 0.9 mg/mL
Immunogen: Fusion protein of human KRR1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only