Ku-80 (Acetyl Lys565) rabbit pAb - ES15226

Ku-80 (Acetyl Lys565) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES15226-50, ES15226-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

Alternate Name: X-ray repair cross-complementing protein 5 (EC 3.6.4.-; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))

Source: Rabbit

Applications: IHC; IF; WB

Dilution: IHC-p 1:50-200, WB 1:500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human Ku-80 (Acetyl-Lys565)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 82kD

Human Gene ID: 7520

Human SWISS Prot NO: P13010

Subcellular Location: Nucleus. Nucleus, nucleolus. Chromosome.

Research Use Only