Ku-80 Monoclonal Antibody - RA11590

Ku-80 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11590-50, RA11590-100

Citations, Manuals and MSDS Available upon request.

Background: X-ray repair cross complementing 5 (XRCC5) Homo sapiens The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF/ICC; FCM; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 7520

SWISS: P13010

Source: Mouse

Research Use Only