Ku-80 Polyclonal Antibody - RA26747

Ku-80 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26747-50, RA26747-100

Citations, Manuals and MSDS Available upon request.

Background: X-ray repair cross complementing 5 (XRCC5) Homo sapiens The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-200, WB 1:500-2000

Alternative Names: X-ray repair cross-complementing protein 5 (EC 3.6.4.-;86 kDa subunit of Ku antigen;ATP-dependent DNA helicase 2 subunit 2;ATP-dependent DNA helicase II 80 kDa subunit;CTC box-binding factor 85 kDa subunit;CTC85;CTCBF;DNA repair protein XRCC5;Ku80;Ku86;Lupus Ku autoantigen protein p86;Nuclear factor IV;Thyroid-lupus autoantigen;TLAA;X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))

Applications: IHC-p; IF (paraffin section) ; WB

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 7520

Protein MW (KDa): 82

SWISS: P13010

Source: Rabbit

Research Use Only