Ku80 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24867-20, A24867-100
Citations, Manuals and MSDS Available upon request.
Background: Predicted to enable several functions, including nucleic acid binding activity; protein C-terminus binding activity; and ubiquitin protein ligase binding activity. Predicted to contribute to 5'-deoxyribose-5-phosphate lyase activity and double-stranded telomeric DNA binding activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; hematopoietic stem cell differentiation; and positive regulation of neurogenesis. Located in cytoplasm and nucleus. Is expressed in thymus primordium. Human ortholog (s) of this gene implicated in chronic obstructive pulmonary disease and multiple myeloma. Orthologous to human XRCC5 (X-ray repair cross complementing 5) .
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, IHC-P, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 83kDa
Observed Molecular Weight: 83kDa
Immunogen: Recombinant protein (or fragment) .
Species: Mouse
GeneID: 22596
SWISS: P27641
Alternate Names: Ku80; Ku86; CTC85; CTCBF
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:100-1:400 IHC-P, 1:2000 - 1:8000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics and Nuclear Signaling DNA / RNA DNA Damage & Repair.
NCBI Alias: Xrcc5
Research Use Only