KV1.1 Polyclonal Antibody - BT-AP04904

KV1.1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04904-20, BT-AP04904-50, BT-AP04904-100

Citations, Manuals and MSDS Available upon request.

Background: KCNA1 encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. Potassium voltage-gated channel subfamily A member 1 has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Research Areas: Neuroscience

Target Protein: KCNA1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: KV1.1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 56542

UniProt Accession: Human: Q09470; Mouse: P16388; Rat: P10499

Synonyms: KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K(+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1

GeneID: Human: 3736; Mouse: 16485; Rat: 24520

Research Use Only