Product Description

Kv1.6 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65717-50, BS65717-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellμlar distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2, KV1.4, KV1.5 and KV1.6) expressed in rat and human brain, suggesting that the individual protein subunits are highly regμlated to control for the assembly and formation of functional neuronal channels.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Pig, Rabbit, Sheep

Host: Rabbit

Applications: WB

Alternate Names: HBK 2, HBK2, Human brain potassium channel 2, KCNA 6, Kcna6, KCNA6_HUMAN, KV1.6, potassium voltage gated channel shaker related subfamily member 6, potassium voltage gated channel subfamily A member 6, Potassium voltage-gated channel subfamily A member 6, voltage gated potassium channel protein Kv1.6, Voltage gated potassium channel subunit Kv1.6, Voltage-gated potassium channel HBK2, Voltage-gated potassium channel subunit Kv1.6.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human Kv1.6:301-400/529 

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: Kv1.6 Polyclonal Antibody detects endogenous levels of Kv1.6 protein.

Molecular Weight: 59 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P17658

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only