Product Description

Kv1.6 Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65717-50, BS65717-100

Swiss-Prot: P17658

Host: Rabbit

Kv1.6 Polyclonal Antibody-BS65717

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Chicken, Pig, Rabbit, Sheep,

Applications: WB,

All Applications: WB=1:500-2000

Background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2, KV1.4, KV1.5 and KV1.6) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.

Purification and Purity: affinity purified by Protein A

Specificity: Kv1.6 Polyclonal Antibody detects endogenous levels of Kv1.6 protein.

Bioworld Molecular Weight: 59 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti- Kv1.6 at 1/1000 dilution, Primary: Anti- Kv1.6 at 1/1000 dilution

Alternative Name: HBK 2; HBK2; Human brain potassium channel 2; KCNA 6; Kcna6; KCNA6_HUMAN; KV1.6; potassium voltage gated channel shaker related subfamily member 6; potassium voltage gated channel subfamily A member 6; Potassium voltage-gated channel subfamily A member 6; voltage gated potassium channel protein Kv1.6; Voltage gated potassium channel subunit Kv1.6; Voltage-gated potassium channel HBK2; Voltage-gated potassium channel subunit Kv1.6.

Immunogen: KLH conjugated synthetic peptide derived from human Kv1.6:301-400/529 

Modification: Unmodified

Conjugate: Unconjugated