Product Description

KV10.1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5772-50, BS5772-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Voltage-gated potassium channels play an essential role in controlling cellμlar excitability in the nervous system. They regμlate a variety of properties including membrane potential as well as the frequency and structure of action potentials. KCNH1 (potassium voltage-gated channel, subfamily H (eag-related), member 1), also known as ether-a-go-go potassium channel 1, voltage-gated potassium channel subunit Kv10.1, EAG, EAG1 or h-eag, is a 989 amino acid mμlti-pass membrane protein belonging to the potassium channel family and H (Eag) subfamily. KCNH1 is highly expressed in myoblasts and brain, forms two alternatively spliced isoforms and exists as a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. Encoded by a gene located on human chromosome 1, KCNH1 forms a heteromμltimer with KCNH5 and also interacts with ALG10.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Potassium voltage-gated channel subfamily H member 1, Ether-a-go-go potassium channel 1, EAG channel 1, h-eag, hEAG1, Voltage-gated potassium channel subunit Kv10.1, KCNH1, EAG, EAG1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 762-807 of Human KV10.1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: KV10.1 polyclonal antibody detects endogenous levels of KV10.1 protein.

Molecular Weight: ~ 111 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O95259

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only