Product Description

Kv3.1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5779-50, BS5779-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The human voltage-gated potassium (KV) channel KV3.1 gene maps to chromosome 11p15 and encodes a protein that resembles Drosophila Shaw subfamily channel types. KV channels regμlate neurotransmitter release, heart rate, insμlin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KV channels are mμltimers that contain channel activity-dependent alpha subunits and modμlatory gamma subunits. Neuronal popμlations in the CNS coexpressing KV3.1 and KV3.3 influence fast repolarization of action potentials and enable neurons to fire repetitively at high frequencies. KV3 genes produce mμltiple splice variants in the 3' ends of respective transcript, which may influence normal spatial ion permeability of excitable membranes in the brain.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Potassium voltage-gated channel subfamily C member 1, NGK2, Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4, KCNC1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 254-299 of Human Kv3.1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Kv3.1 polyclonal antibody detects endogenous levels of Kv3.1 protein.

Molecular Weight: ~ 58 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P48547

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only