Product Description

KV4.2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7959-50, BS7959-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellμlar distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming a-subunits (KVα), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KVβ subunits that modify the gating properties of the coexpressed KVα subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2, KV1.4, KV1.5 and KV1.6) expressed in rat and human brain, suggesting that the individual protein subunits are highly regμlated to control for the assembly and formation of functional neuronal channels.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: KCD2, KCND 2, KCND2, KCND2_HUMAN, KIAA1044, MGC119702, MGC119703, Potassium voltage gated channel Shal related subfamily member 2, Potassium voltage-gated channel subfamily D member 2, RK 5, RK5, Voltage gated potassium channel Kv4.2, Voltage gated potassium channel subunit Kv4.2, Voltage sensitive potassium channel, Voltage-gated potassium channel subunit Kv4.2,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human KV4.2.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: KV4.2 polyclonal antibody detects endogenous levels of KV4.2 protein.

Molecular Weight: ~ 82 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NZV8

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only