Product Description

Kv5.1 Polyclonal Antibody

Catalogue Numbers: BS62431-50, BS62431-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: Q9H3M0

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

All Applications: WB:1:500~1:1000

Background: KCNF1 (potassium voltage-gated channel subfamily F member 1) is a multipass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.

Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity: Kv5.1 polyclonal antibody detects endogenous levels of Kv5.1 protein.

Extra Notes: Western blot (WB) analysis of Kv5.1 polyclonal antibody at 1:500 dilution
LaneA:COS-7 whole cell lysate
LaneB:Panc1 whole cell lysate
LaneC:The heart tissue lysate of Mouse
LaneD:The heart tissue lysate of Rat

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Potassium voltage-gated channel subfamily F member 1; Voltage-gated potassium channel subunit Kv5.1; Kh1; KCNF1

Immunogen: Synthetic peptide, corresponding to Human Kv5.1.

Conjugate: Unconjugated

Modification: Unmodified